Who We Are

TrueBinding Inc. is a clinical-stage biotherapeutics company pioneering a broad-spectrum healthspan platform. Rather than chasing downstream symptoms, we are dedicated to resolving the fundamental drivers of chronic inflammation and age-related decline. By targeting these upstream mechanisms, we are developing transformative treatments for neurodegeneration (Alzheimer's, Parkinson's), stroke, fibrosis, and oncology.

At the heart of our innovation is the TrueBinding™ platform, a proprietary discovery engine focused on the body's 'Master Switches' of disease and aging—most notably, Galectin-3 (Gal-3). By neutralizing Gal-3, our platform halts the toxic feedback loops of neuroinflammation, protein aggregation, and systemic tissue damage. This single, highly validated biological target powers our development of potentially game-changing monoclonal antibodies.

Our ultimate vision extends beyond treating late-stage disease; by restoring immune balance and protecting cellular integrity, TrueBinding is building the ultimate platform to extend human healthspan and longevity.

Meet The Team

We are scientists, physicians, and drug developers

George Hong,
Interim-CEO

•Founder of TrueBinding (2016), committed to discovering novel targets for innovative treatments.

• Established success in healthcare investment, with strategic investments in high-impact companies such as Ceribell, Neurovasc, Arrinex, Devoro, and Lucira.

Rajesh Pahwa, MD

  • Chief of the Parkinson's and Movement Disorder Division and director of Parkinson Foundation Center of Excellence at the University of Kansas Medical Center. (more)

Alan K Jacobs, MD
CMO

  • CMO Satellos Biosciences

  • VP of clinical development at Boston Pharmaceuticals and Immunovant

  • Director of clinical development at Sanofi Genzyme

  • 40+ years of experience in clinical development (more)

Fan Chen, PhD SVP of CMC and GMP• 20+ years of experience in Bioprocess Development • Senior Leaders at LakePharma, Dendreon and MedImmune

Fan Chen, PhD
COO

• 20+ years of experience in Bioprocess Development
• Senior Leadership positions at AstraZeneca, LakePharma, Dendreon and MedImmune

Charles Glabe, PhD

  • Distinguished professor at UCI and a pioneer in Amyloid pathogenesis  (more)

Mitchel Berger, MD• Chair of neurological surgery department at UCSF • President, American Association of Neurological Surgeons

Mitchel Berger, MD

  • Chair of neurological surgery department at UCSF

  • President, American Association of Neurological Surgeons (more)

Brian Z. Ring, PhD
CDO

•25+ years of leadership in bioinformatics and personalized medicine

•Chief Scientific Officer for biotech innovators

•Stanford Professor (more)