On 04/23/2021 FDA clears Truebinding IND application for TB006 in treatment of  Alzheimer's patients!




Company News!

On 04/23/2021 FDA Grants Clearance of IND Application to TB006 for the Treatment of Alzheimer’s Disease

On 03/09/2021 FDA Clears IND Application for TB006 for COVID-19 patients


TrueBinding Inc. is a clinical stage biotherapeutic company focusing on creating new and exciting molecules for applications in immuno-oncology and other disease areas with great unmet medical need including neurological disorders and neurodegenerative diseases.

Based on the application of the Truebinding™ platform, TrueBinding has to date discovered over 6 novel ligands, previously uncharacterized, to receptors of known checkpoint inhibitor pathways.



Our proprietary TrueBindingTM technology is proven to be a powerful tool to discover new targets and their binding partners. Our technology is superior to other traditional approaches. The novel interactions identified by TrueBindingTM technology are confirmed in various in vitro and in vivo assays. TrueBinding, Inc has over sixteen patent applications in its portfolio protecting discoveries and their utility.



TrueBinding, Inc has a number of programs in its portfolio at different stages of development.  



Dr. Dongxu Sun
Co-founder &  CEO

Lead discovery efforts at ImmuNext

Successfully identified new protein binding interactions in cytokine signaling pathways

Project Scientist at Cleveland Clinic

Postdoctoral training at Cornell Medical College

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Dr. Fan Chen
SVP of CMC and GMP

20+ years of experience in Bioprocess Development

VP of Process Development at LakePharma

Senior Leader of Process Development at Dendreon and MedImmune

MD.  Thomas Wisniewski

Director of Alzheimer’s Disease Center

NYU School of Medicine

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Dr.  Charles Glabe

Distinguished professor at UCI and a pioneer in Amyloid pathogenesis. 

Fellows of National Academy of Inventors and AAAS

PhD. MD.  Adam Boxer

Director of Neurosciences

Clinical Research at UCSF

MD.  Mitchel Berger

Chair of neurological surgery department at UCSF

Director of the Brain Tumor Research Center

President, American Association of Neurological Surgeons

President, American Academy of Neurological Surgery

Professor Debbie Thurmond

Key opinion leader in the field of Diabetes and Metabolism. 

Founding Chair of the Department of Molecular & Cellular Endocrinology at the City of Hope Beckman Research Institute

Deputy Director of the Diabetes & Metabolism Research Institute

Lab Work


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